Medication-Assisted Treatment

What is Methadone Maintenance Treatment?

Fiona Kennedy
Written byFiona Kennedy
Dr Olalekan Otulana
Medically Reviewed by Dr Olalekan Otulana MBChB, MRCGP, FRSPH, MBA Addiction Specialist Physician
Last updated:
15 July 2025

Methadone is a synthetic opioid, which has been used as a substitute treatment for many years.  It has several properties that make it an excellent substitute for other opioids and heroin in particular. 

These include a long duration of action so it can be taken once daily; is available in liquid form which deters injecting; having a relatively little euphoriant effect, thus eliminating withdrawal symptoms without reinforcing continued use.

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